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Below is one of our free research papers on DQ8. If the term paper below is not exactly what you're looking for, you can search our essay database for other topics.
you know that DQ8 is one of the two major genes which may lead to celiac disease. You may also know that celiac disease is often associated with various other autoimmune diseases. What you may not know is that DQ8 may be the direct cause of these other autoimmune diseases, for these autoimmune diseases are found in increased incidence not just in celiac disease, but also with DQ8 itself.
What follows is a list I have compiled showing the various diseases that are found in increased frequency among people who have the DQ8 gene (DQB1*0302). I will show the reference number next to each, and the corresponding references will appear below: Celiac disease (1) Scleroderma (2) Rheumatoid arthritis (1) Autoimmune thyroiditis (3) Pemphigus (4) Lupus (6) Pemphigoid (5) Focal myositis (7) Multiple sclerosis (8) Myasthenia gravis (1) Insulin dependant latent autoimmune diabetes of adults and adult Type 1 diabetes (9) Type 1 juvenile diabetes (1) Sjogrenˇ¦s syndrome (10) Addisonsˇ¦s disease (11) Complex regional pain syndrome with dystonia (12) Latex allergy (13) This list is not intended to be exhaustive. It is a starter list. Hopefully more research will be done on these, including carefully controlled research as to whether gluten plays any role in triggering these other autoimmune diseases even in the absence of gluten blood antibodies or positive duodenal biopsies. I, for one have DQ8 and numerous of these autoimmune diseases, even though my gluten blood antib...
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